Article
[Analysis of NF2 gene mutations in intraspinal Schwannomas].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Oct 2017
Liu Shuyi, Chen Shi, Zhang Kaichuang, Lin Jian, Yang Qingwu, Zhang Yongliang, Liu Shuiyuan, Liu Shengze
Abstract excerpt
OBJECTIVE: To explore the correlation between intraspinal Schwannomas and mutations of the NF2 gene. METHODS: Samples from 20 patients with sporadic intraspinal Schwannomas were collected and subjected NF2 gene mutation detection by PCR amplification and Sanger sequencing. RESULTS: Four de novo frameshifting mutations of the NF2 gene were discovered in the tumor tissues, which included...
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