Clostridium difficile, Aging, and the Gut: Can Microbiome Rejuvenation Keep Us Young and Healthy?

Abstract excerpt

(See the major article by de Shin et al, on pages 188–97.) One of the most important risk factors for mortality with Clostridium difficile infection (CDI) is age. Elderly patients experience more severe disease, more frequent recurrences and higher mortality rates than younger patients [1]. In addressing possible explanations for this age effect, one might consider the causative agent, as well as attributes of...

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