Aging-Associated Augmentation of Gut Microbiome Virulence Capability Drives Sepsis Severity

Abstract excerpt

Older adults suffer more frequent and worse outcomes from sepsis, a critical illness secondary to infection. The reasons underlying this unique susceptibility are incompletely understood. Prior work in this area has focused on how the immune response changes with age. The current study, however, focuses instead on alterations in the community of bacteria that humans live with within their gut (i.e., the gut...

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