Article
A dual targeted β-defensin and exome sequencing approach to identify, validate and functionally characterise genes associated with bull fertility.
Scientific reports - 25 Sept 2017
Whiston Ronan, Finlay Emma K, McCabe Matthew S, Cormican Paul, Flynn Paul, Cromie Andrew, Hansen Peter J, Lyons Alan, Fair Sean, Lonergan Patrick, O' Farrelly Cliona, Meade Kieran G
Abstract excerpt
Bovine fertility remains a critical issue underpinning the sustainability of the agricultural sector. Phenotypic records collected on >7,000 bulls used in artificial insemination (AI) were used to identify 160 reliable and divergently fertile bulls for a dual strategy of targeted sequencing (TS) of fertility-related β-defensin genes and whole exome sequencing (WES). A haplotype spanning multiple β-defensin genes...
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