Article
Genomic analysis of codon usage shows influence of mutation pressure, natural selection, and host features on Senecavirus A evolution.
Microbial pathogenesis - 1 Nov 2017
Chen Ye, Xu Quanming, Tan Chen, Li Xinxin, Chi Xiaojuan, Cai Binxiang, Yu Ziding, Ma Yanmei, Chen Ji-Long
Abstract excerpt
Senecavirus A (SVA) infection was recently confirmed in pigs in Brazil, United States of America and Canada. To better understand the molecular characteristics of isolated SVA genomes, we first reported genome-wide comprehensive analyses of codon usage and various factors that have contribute to the molecular evolution in SVA. The effective number of codons (ENC) ranged from 54.51 to 55.54 with an average of...
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