Article
Aortic Valve Stenosis Alters Expression of Regional Aortic Wall Shear Stress: New Insights From a 4-Dimensional Flow Magnetic Resonance Imaging Study of 571 Subjects.
Journal of the American Heart Association - 13 Sept 2017
van Ooij Pim, Markl Michael, Collins Jeremy D, Carr James C, Rigsby Cynthia, Bonow Robert O, Malaisrie S Chris, McCarthy Patrick M, Fedak Paul W M, Barker Alex J
Abstract excerpt
BACKGROUND: Wall shear stress (WSS) is a stimulus for vessel wall remodeling. Differences in ascending aorta (AAo) hemodynamics have been reported between bicuspid aortic valve (BAV) and tricuspid aortic valve patients with aortic dilatation, but the confounding impact of aortic valve stenosis (AS) is unknown. METHODS AND RESULTS: Five hundred seventy-one subjects underwent 4-dimensional flow magnetic resonance...
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