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Article

Genetic variation in the MITF promoter affects skin colour and transcriptional activity in black-boned chickens.

British poultry science - 1 Feb 2018

Wang G, Liao J, Tang M, Yu S

Abstract excerpt

1. Microphthalmia-associated transcription factor (MITF) plays a pivotal role in melanocyte development by regulating the transcription of major pigmentation enzymes (e.g. TYR, TYRP1 and DCT). A single-nucleotide polymorphism (SNP), c.-638T>C, was identified in the MITF promoter, and genotyping of a population (n = 426) revealed that SNP c.-638T>C was associated with skin colour in black-boned chickens. 2....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microphthalmia-Associated Transcription Factor

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 28891677
DOI: 10.1080/00071668.2017.1379053

Genes

MITF
TYR
DCT
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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