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Article

Single Stem Cell Imaging and Analysis Reveals Telomere Length Differences in Diseased Human and Mouse Skeletal Muscles.

Stem cell reports - 10 Oct 2017

Tichy Elisia D, Sidibe David K, Tierney Matthew T, Stec Michael J, Sharifi-Sanjani Maryam, Hosalkar Harish, Mubarak Scott, Johnson F Brad, Sacco Alessandra, Mourkioti Foteini

Abstract excerpt

Muscle stem cells (MuSCs) contribute to muscle regeneration following injury. In many muscle disorders, the repeated cycles of damage and repair lead to stem cell dysfunction. While telomere attrition may contribute to aberrant stem cell functions, methods to accurately measure telomere length in stem cells from skeletal muscles have not been demonstrated. Here, we have optimized and validated such a method,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle Fibers, Skeletal

Share to Muscular Dystrophy, Duchenne

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Source

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Identifiers

PMID: 28890163
DOI: 10.1016/j.stemcr.2017.08.003
PMCID: PMC5639167

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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