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Article

No evidence for a role of the serotonin 4 receptor in five-factor personality traits: A positron emission tomography brain study.

PloS one - 1 Jan 2017

Stenbæk Dea Siggaard, Dam Vibeke Høyrup, Fisher Patrick MacDonald, Hansen Nanna, Hjordt Liv Vadskjær, Frokjaer Vibe Gedsoe

Abstract excerpt

Serotonin (5-HT) brain architecture appears to be implicated in normal personality traits as supported by genetic associations and studies using molecular brain imaging. However, so far, no studies have addressed potential contributions to variation in normal personality traits from in vivo serotonin 4 receptor (5-HT4R) brain availability, which has recently become possible to image with Positron Emission...

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PMID: 28880910
DOI: 10.1371/journal.pone.0184403
PMCID: PMC5589219

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