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Article

CXCL12 overexpression promotes the angiogenesis potential of periodontal ligament stem cells.

Scientific reports - 31 Aug 2017

Zhang Lei, Zhou Yong, Sun Xiaoyu, Zhou Jian, Yang Pishan

Abstract excerpt

Periodontal ligament stem cells (PDLSCs) are a major source of mesenchymal stem cells (MSCs) in adults and are effective for tissue engineering, like promoting angiogenesis and bone regeneration. CXCL12 has been reported to be involved in the recruitment and engraftment of MSCs in wound sites. However, whether CXCL12 potentiates the angiogenesis of PDLSCs is not clear. In this experiment, we transduced PDLSCs...

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Share to Bone Regeneration
Share to Chemokine CXCL12
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mesenchymal Stem Cells

Share to Neovascularization, Physiologic

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Source

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Identifiers

PMID: 28860570
DOI: 10.1038/s41598-017-10971-1
PMCID: PMC5579269

Genes

CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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