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Seven-CpG-based prognostic signature coupled with gene expression predicts survival of oral squamous cell carcinoma

24 Aug 2017

Abstract excerpt

DNA methylation has started a recent revolution in genomics biology by identifying key biomarkers for multiple cancers, including oral squamous cell carcinoma (OSCC), the most common head and neck squamous cell carcinoma. A multi-stage screening strategy was used to identify DNA-methylation-based signatures for OSCC prognosis. We used The Cancer Genome Atlas (TCGA) data as training set which were validated in two...

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PMID: 28852427
DOI: 10.1186/s13148-017-0392-9

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