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Microbial Lineages in Sarcoidosis. A Metagenomic Analysis Tailored for Low–Microbial Content Samples

28 Aug 2017

Abstract excerpt

RATIONALE: The etiology of sarcoidosis is unknown, but microbial agents are suspected as triggers. OBJECTIVES: We sought to identify bacterial, fungal, or viral lineages in specimens from patients with sarcoidosis enriched relative to control subjects using metagenomic DNA sequencing. Because DNA from environmental contamination contributes disproportionately to samples with low authentic microbial content, we...

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Share to Antifungal resistance and susceptibility
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 28846439
DOI: 10.1164/rccm.201705-0891oc

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