Article
Major surgery diminishes systemic arginine availability and suppresses nitric oxide response to feeding in patients with early stage breast cancer.
Clinical nutrition (Edinburgh, Scotland) - 1 Oct 2018
Engelen Mariëlle P K J, Klimberg V Suzanne, Allasia Arianna, Deutz Nicolaas E P
Abstract excerpt
BACKGROUND & AIMS: Plasma arginine (ARG) levels are reduced in breast cancer, suggesting diminished systemic ARG availability. ARG and its product nitric oxide (NO) are important in early postoperative recovery due to its roles in immune function and wound healing. It remains unclear whether major surgery further diminishes systemic ARG availability due to enhanced ARG catabolism and/or insufficient endogenous...
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