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Article

Losartan in combination with propranolol slows the aortic root dilatation in neonatal Marfan syndrome.

Pediatrics and neonatology - 1 Apr 2018

Liu Lu-Hang, Lin Shan-Miao, Lin Dar-Shong, Chen Ming-Ren

Abstract excerpt

Neonatal Marfan syndrome, in contrast to classical Marfan syndrome, is characterized by rapidly progressive multi-valvular cardiac disease and death from congestive heart failure, typically within the first year of life. Due to the rarity of this condition, treatment for neonatal Marfan syndrome has not been well studied. In this report, a combination of losartan and propranolol reduced the aortic root dilatation...

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Source

Identifiers

PMID: 28823387
DOI: 10.1016/j.pedneo.2017.07.005

Genes

FBN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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