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Article

Interactions Between Variation in Candidate Genes and Environmental Factors in the Etiology of Schizophrenia and Bipolar Disorder: a Systematic Review.

Molecular neurobiology - 1 Jun 2018

Misiak Błażej, Stramecki Filip, Gawęda Łukasz, Prochwicz Katarzyna, Sąsiadek Maria M, Moustafa Ahmed A, Frydecka Dorota

Abstract excerpt

Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with high heritability rates. The contribution of genetic factors to the etiology of these disorders is increasingly being recognized as the action of multiple risk variants with small effect sizes, which might explain only a minor part of susceptibility. On the other site, numerous environmental factors have been found to play an...

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Source

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Identifiers

PMID: 28822116
DOI: 10.1007/s12035-017-0708-y
PMCID: PMC5948257

Genes

BDNF
COMT
FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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