Article
Autoantibodies against "rods and rings"-related IMPDH2 in hepatitis C genotype 1 and DAA therapy in a "real life" cohort.
Medical microbiology and immunology - 1 Oct 2017
Dammermann Werner, Polywka Susanne, Dettmann Inga, Mindorf Swantje, Komorowski Lars, Wehmeyer Malte, Schulze Zur Wiesch Julian, Stöcker Winfried, Lüth Stefan
Abstract excerpt
Autoantibodies against inosine-5'-monophosphate-dehydrogenase-2 (IMPDH2; "rods and rings" pattern) develop in chronic hepatitis C (CHC) patients under treatment with peg-interferon (IFN) and ribavirin (RBV), an inhibitor of IMPDH2. We investigated the influence of the alternative therapy with direct-acting antivirals (DAA)/ribavirin on anti-IMPDH2 autoantibody generation and the use of anti-IMPDH2 development as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.