Article
The SNP-set based association study identifies ITGA1 as a susceptibility gene of attention-deficit/hyperactivity disorder in Han Chinese.
Translational psychiatry - 15 Aug 2017
Liu L, Zhang L, Li H M, Wang Z R, Xie X F, Mei J P, Jin J L, Shi J, Sun L, Li S C, Tan Y L, Yang L, Wang J, Yang H M, Qian Q J, Wang Y F
Abstract excerpt
Genome-wide association studies, which detect the association between single-nucleotide polymorphisms (SNPs) and disease susceptibility, have been extensively applied to study attention-deficit/hyperactivity disorder (ADHD), but genome-wide significant associations have not been found yet. Genetic heterogeneity and insufficient genomic coverage may account for the missing heritability. We performed a two-stage...
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