Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating the Genetic Causes of Sudden Unexpected Death in Children Through Targeted Next-Generation Sequencing Analysis.

Circulation. Cardiovascular genetics - 1 Aug 2017

Dewar Laura J, Alcaide Miguel, Fornika Daniel, D'Amato Luisa, Shafaatalab Sanam, Stevens Charles M, Balachandra Thambirajah, Phillips Susan M, Sanatani Shubhayan, Morin Ryan D, Tibbits Glen F

Abstract excerpt

BACKGROUND: Inherited arrhythmia syndromes are responsible for a significant portion of autopsy-negative sudden unexpected death (SUD) cases, but molecular autopsy used to identify potentially causal variants is not routinely included in SUD investigations. We collaborated with a medical examiner's office to assist in finding a diagnosis for their autopsy-negative child SUD cases. METHODS AND RESULTS: 191 child...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arrhythmias, Cardiac
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Death, Sudden, Cardiac

Share to High-Throughput Nucleotide Sequencing

Share to Infant, Newborn

Share to Plakophilins

Share to Sodium-Calcium Exchanger

Share to Troponin I

Source

Identifiers

PMID: 28807990
DOI: 10.1161/CIRCGENETICS.116.001738

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating the Genetic Causes of Sudden Unexpected Death in Children Through Targeted Next-Generation Sequencing Analysis.PMID 28807990Read ↗

Exome analysis focusing on epilepsy-related genes in children and adults with sudden unexplained deathSemantic proximity Read ↗

The impact of damaging epilepsy and cardiac genetic variant burden in sudden death in the youngSemantic proximity Read ↗

Cardiac channelopathy testing in 274 ethnically diverse sudden unexplained deaths.Semantic proximity Read ↗

Systematic Review of the Genetics of Sudden Unexpected Death in Epilepsy: Potential Overlap With Sudden Cardiac Death and Arrhythmia-Related Genes.Semantic proximity Read ↗

The impact of damaging epilepsy and cardiac genetic variant burden in sudden death in the youngSemantic proximity Read ↗

Genetic Determinants of Sudden Unexpected Death in Pediatrics.Semantic proximity Read ↗

Postmortem Identification of Genetic Variations Associated with Sudden Unexpected Death in Young People.Semantic proximity Read ↗

Genetic investigations of sudden unexpected deaths in infancy using next-generation sequencing of 100 genes associated with cardiac diseases.Semantic proximity Read ↗

High‐resolution molecular genomic autopsy reveals complex sudden unexpected death in epilepsy risk profileSemantic proximity Read ↗

Post-mortem whole-exome sequencing (WES) with a focus on cardiac disease-associated genes in five young sudden unexplained death (SUD) cases.Semantic proximity Read ↗

Importance of Variant Interpretation in Whole-Exome Molecular Autopsy: Population-Based Case Series.Semantic proximity Read ↗

Exome-based analysis of cardiac arrhythmia, respiratory control, and epilepsy genes in sudden unexpected death in epilepsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.