Article
Evidence against Ha-ras-1 involvement in sporadic and familial melanoma.
Nature - 1 Jan 2000
Gerhard D S, Dracopoli N C, Bale S J, Houghton A N, Watkins P, Payne C E, Greene M H, Housman D E
Abstract excerpt
It was recently reported that different rare alleles at the Ha-ras-1 locus occurred at a significantly higher combined frequency in cancer patients than in an unaffected population. In particular, melanoma patients were reported to have a significantly higher frequency of such alleles. We have examined the frequency of rare Ha-ras-1 alleles in a large number of cases of sporadic melanoma. Our results indicate...
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