Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasmid-mediated mcr-1 colistin resistance in Escherichia coli and Klebsiella spp. clinical isolates from the Western Cape region of South Africa

3 Aug 2017

Abstract excerpt

Colistin is a last resort antibiotic for the treatment of carbapenem-resistant Gram negative infections. Until recently, mechanisms of colistin resistance were limited to chromosomal mutations which confer a high fitness cost and cannot be transferred between organisms. However, a novel plasmid-mediated colistin resistance mechanism, encoded by the mcr-1 gene, has been identified, and has since been detected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Antibiotics Pharmacokinetics and Efficacy
Share to Pharmaceutical and Antibiotic Environmental Impacts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28785405
DOI: 10.1186/s13756-017-0234-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasmid-mediated mcr-1 colistin resistance in Escherichia coli and Klebsiella spp. clinical isolates from the Western Cape region of South AfricaPMID 28785405Read ↗

Colistin Resistance Mechanisms in Clinical Escherichia coli and Klebsiella spp. Isolates from the Western Cape of South Africa.Semantic proximity Read ↗

Genetic Features of mcr-1 Mediated Colistin Resistance in CMY-2-Producing Escherichia coli From Romanian PoultrySemantic proximity Read ↗

Prevalence and molecular characteristics of mcr-1 colistin resistance in Escherichia coli: isolates of clinical infection from a Chinese University HospitalSemantic proximity Read ↗

Dissemination of clinical Escherichia coli harboring the mcr-1 gene in PakistanSemantic proximity Read ↗

Detection of Plasmid Mediated Colistin Resistant mcr-1 Gene Among Escherichia Coli and Klebsiella Pneumoniae Isolated From Clinical SamplesSemantic proximity Read ↗

Analysis of mcr family of colistin resistance genes in Gram-negative isolates from a tertiary care hospital in IndiaSemantic proximity Read ↗

Heterogeneous and Flexible Transmission of mcr-1 in Hospital-Associated Escherichia coli.Semantic proximity Read ↗

Characterisation of colistin resistance in Gram-negative microbiota of pregnant women and neonates in NigeriaSemantic proximity Read ↗

The first report of the mobile colistin resistance gene, mcr-10.1, in Kenya and a novel mutation in the phoQ gene (S244T) in a colistin-resistant Enterobacter cloacae clinical isolate.Semantic proximity Read ↗

Prevalence and characteristics of multidrug-resistant mcr-1-positive Escherichia coli isolates from broiler chickens in Tai'an, ChinaSemantic proximity Read ↗

Mobile Colistin-Resistant Genes mcr-1, mcr-2, and mcr-3 Identified in Diarrheal Pathogens among Infants, Children, and Adults in Bangladesh: Implications for the FutureSemantic proximity Read ↗

Molecular Mechanisms of Colistin Resistance in Klebsiella pneumoniae in a Tertiary Care Teaching HospitalSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.