Article
Key features of invasive pneumococcal isolates recovered in Lima, Peru determined through whole genome sequencing.
International journal of medical microbiology : IJMM - 1 Oct 2017
Hawkins Paulina, Mercado Erik, Chochua Sopio, Castillo Maria E, Reyes Isabel, Chaparro Eduardo, Gladstone Rebecca, Bentley Stephen D, Breiman Robert F, Metcalf Benjamin J, Beall Bernard, Ochoa Theresa J, McGee Lesley
Abstract excerpt
Before PCV7 introduction, invasive pneumococcal disease (IPD) was responsible for approximately 12,000-18,000 deaths annually among children <5years in Latin America. In Peru, PCV7 was introduced in 2009. We used whole genome sequencing to deduce key features of invasive strains collected in Lima, Peru from 2006 to 2011. We sequenced 212 IPD isolates from 16 hospitals in Lima pre (2006-2009; n=133) and post...
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