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Article

mTOR deregulation in oral cavity squamous cell carcinoma.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000

Mastronikolis Nicholas S, Tsiambas Evangelos, Papadas Theodoros A, Fotiades Panagiotis P, Papadas Athanasios T, Mastronikolis Stylianos N, Kastanioudakis Ioannis, Ragos Vasileios

Abstract excerpt

Signal transduction pathways consist of a variety of inter- and intra-cellular molecules. They act as supporting mechanisms for cell survival and homeostasis. Among them, the phosphatidylinositol 3-kinase (PI3K)/tumor suppressor phosphatase and tensin homologue deleted on chromosome ten (PTEN)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway plays a crucial role in regulating normal cell growth...

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PMID: 28730764

Genes

PTEN

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