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Molecular Mechanisms of Human Papillomavirus Induced Skin Carcinogenesis

14 Jul 2017

Abstract excerpt

Infection of the cutaneous skin with human papillomaviruses (HPV) of genus betapapillomavirus (βHPV) is associated with the development of premalignant actinic keratoses and squamous cell carcinoma. Due to the higher viral loads of βHPVs in actinic keratoses than in cancerous lesions, it is currently discussed that these viruses play a carcinogenic role in cancer initiation. In vitro assays performed to...

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PMID: 28708084
DOI: 10.3390/v9070187

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