Article
Diversity of Pneumocystis jirovecii Across Europe: A Multicentre Observational Study.
EBioMedicine - 1 Aug 2017
Alanio Alexandre, Gits-Muselli Maud, Guigue Nicolas, Desnos-Ollivier Marie, Calderon Enrique J, Di Cave David, Dupont Damien, Hamprecht Axel, Hauser Philippe M, Helweg-Larsen Jannik, Kicia Marta, Lagrou Katrien, Lengerova Martina, Matos Olga, Melchers Willem J G, Morio Florent, Nevez Gilles, Totet Anne, White Lewis P, Bretagne Stéphane
Abstract excerpt
Pneumocystis jirovecii is an airborne human-specific ascomycetous fungus responsible for Pneumocystis pneumonia (PCP) in immunocompromised patients, affecting >500,000 patients per year (www.gaffi.org). The understanding of its epidemiology is limited by the lack of standardised culture. Recent genotyping data suggests a limited genetic diversity of P. jirovecii. The objective of the study was to assess the...
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