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Article

Familial Associations of Colorectal Cancer with Other Cancers.

Scientific reports - 12 Jul 2017

Yu Hongyao, Hemminki Akseli, Sundquist Kristina, Hemminki Kari

Abstract excerpt

Colorectal cancer (CRC) has a strong familial component which extends to discordant cancers (ie non-CRC tumors). This is best seen in cancer syndromes such as hereditary non-polyposis colorectal cancer (HNPCC) which predisposes to several tumor types. Population-based family studies have also found discordant associations for CRC but they have included cancers which manifest in HNPCC, and there is no convincing...

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Identifiers

PMID: 28701784
DOI: 10.1038/s41598-017-05732-z
PMCID: PMC5507930

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