Article
ACE: an efficient and sensitive tool to detect insecticide resistance-associated mutations in insect acetylcholinesterase from RNA-Seq data.
BMC bioinformatics - 10 Jul 2017
Guo Dianhao, Luo Jiapeng, Zhou Yuenan, Xiao Huamei, He Kang, Yin Chuanlin, Xu Jianhua, Li Fei
Abstract excerpt
BACKGROUND: Insecticide resistance is a substantial problem in controlling agricultural and medical pests. Detecting target site mutations is crucial to manage insecticide resistance. Though PCR-based methods have been widely used in this field, they are time-consuming and inefficient, and typically have a high false positive rate. Acetylcholinesterases (Ace) is the neural target of the widely used...
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