Article
Detection of candidate nectin gene mutations in infertile men with severe teratospermia.
Journal of assisted reproduction and genetics - 1 Oct 2017
Bronson Richard, Mikhailik Anatoly, Schwedes John, Gnatenko Dimitri, Hatchwell Eli
Abstract excerpt
PURPOSE: Approximately 40% of infertile men have an abnormal semen analysis, resulting from either abnormalities of sperm production (defective spermatogenesis) or sperm shape (defective spermiogenesis). This latter process is dependent upon the function of Sertoli cells, which maintain specialized junctional complexes with germ cells. Nectins, members of the immunoglobulin superfamily, participate in formation...
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