Article
LGMD2E is the most common type of sarcoglycanopathies in the Iranian population.
Journal of neurogenetics - 1 Sept 2017
Alavi Afagh, Esmaeili Sara, Nilipour Yalda, Nafissi Shahriar, Tonekaboni Seyed Hasan, Zamani Gholamreza, Ashrafi Mahmoud Reza, Kahrizi Kimia, Najmabadi Hossein, Jazayeri Fatemeh
Abstract excerpt
Sarcoglycanopathies (SGCs) which are caused by mutations in SGCA, SGCB, SGCG or SGCD genes are a subgroup of autosomal-recessive limb-girdle-muscular-dystrophies (LGMD2). Although frequencies of mutations in these genes are different among populations, mutations in SGCA and SGCD, respectively, have the highest and lowest frequencies in most populations. Here, we report the proportion of mutations in SGC genes...
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