Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Syncytiotrophoblast derived extracellular vesicles transfer functional placental miRNAs to primary human endothelial cells

27 Jun 2017

Abstract excerpt

During the pregnancy associated syndrome preeclampsia (PE), there is increased release of placental syncytiotrophoblast extracellular vesicles (STBEVs) and free foetal haemoglobin (HbF) into the maternal circulation. In the present study we investigated the uptake of normal and PE STBEVs by primary human coronary artery endothelial cells (HCAEC) and the effects of free HbF on this uptake. Our results show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to MicroRNA in disease regulation
Share to Pregnancy and preeclampsia studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28676635
DOI: 10.1038/s41598-017-04468-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Syncytiotrophoblast derived extracellular vesicles transfer functional placental miRNAs to primary human endothelial cellsPMID 28676635Read ↗

Update of syncytiotrophoblast derived extracellular vesicles in normal pregnancy and preeclampsiaSemantic proximity Read ↗

Preeclampsia and syncytiotrophoblast membrane extracellular vesicles (STB-EVs)Semantic proximity Read ↗

Syncytiotrophoblast extracellular vesicles – Circulating biopsies reflecting placental healthSemantic proximity Read ↗

Role of Extracellular Vesicles and microRNAs on Dysfunctional Angiogenesis during Preeclamptic PregnanciesSemantic proximity Read ↗

Placenta-derived extracellular vesicles: their cargo and possible functionsSemantic proximity Read ↗

Placenta-derived extracellular vesicles from preeclamptic and healthy pregnancies impair ex vivo vascular endothelial functionSemantic proximity Read ↗

Placental extracellular vesicles and pre‐eclampsiaSemantic proximity Read ↗

MicroRNA analysis of medium/large placenta extracellular vesicles in normal and preeclampsia pregnanciesSemantic proximity Read ↗

Placenta-Derived Exosomes and Syncytiotrophoblast Microparticles and their Role in Human Reproduction: Immune Modulation for Pregnancy SuccessSemantic proximity Read ↗

A Cross-Sectional Analysis of Syncytiotrophoblast Membrane Extracellular Vesicles Derived Transcriptomic Biomarkers in PreeclampsiaSemantic proximity Read ↗

Placental Vesicles Carry Active Endothelial Nitric Oxide Synthase and Their Activity is Reduced in PreeclampsiaSemantic proximity Read ↗

Circulating Placental Extracellular Vesicles and Their Potential Roles During PregnancySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.