Article
Edwardsiella piscicida lacking the cyclic AMP receptor protein (Crp) is avirulent and immunogenic in fish.
Fish & shellfish immunology - 1 Sept 2017
Choe Yunjeong, Park Junmo, Yu Jong Earn, Oh Jeong-Il, Kim Suhkmann, Kang Ho Young
Abstract excerpt
Edwardsiella piscicida is a Gram-negative pathogen that generally causes lethal septicemia in marine and freshwater fish. We generated a E. piscicida CK216 Δcrp mutant to investigate various biological roles related to this organism, including pathogenesis. Lack of Crp in CK216 was demonstrated by immunoblotting using a Crp-specific antibody. Compared to the parental strain, the mutant exhibited changes in three...
Topics
- Animals
- Bacterial Proteins
- Cyclic AMP Receptor Protein
- Edwardsiella
- Enterobacteriaceae Infections
- Fish Diseases
- Goldfish
- Mutation
- Virulence
