Article
Double hit of NEMO gene in preeclampsia.
PloS one - 1 Jan 2017
Sakowicz Agata, Pietrucha Tadeusz, Rybak-Krzyszkowska Magda, Huras Hubert, Gach Agnieszka, Sakowicz Bartosz, Banaszczyk Mateusz, Grzesiak Mariusz, Biesiada Lidia
Abstract excerpt
The precise etiology of preeclampsia is unknown. Family studies indicate that both genetic and environmental factors influence its development. One of these factors is NFkB, whose activation depends on NEMO (NFkB essential modulator. This is the first study to investigate the association between the existence of single nucleotide variant of the NEMO gene and the appearance of preeclampsia. A total of 151 women...
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