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Article

Semen amyloids participate in spermatozoa selection and clearance

26 Jun 2017

Abstract excerpt

Unlike other human biological fluids, semen contains multiple types of amyloid fibrils in the absence of disease. These fibrils enhance HIV infection by promoting viral fusion to cellular targets, but their natural function remained unknown. The similarities shared between HIV fusion to host cell and sperm fusion to oocyte led us to examine whether these fibrils promote fertilization. Surprisingly, the fibrils...

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PMID: 28653619
DOI: 10.7554/elife.24888

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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