Article
MinE conformational dynamics regulate membrane binding, MinD interaction, and Min oscillation.
Proceedings of the National Academy of Sciences of the United States of America - 18 Jul 2017
Park Kyung-Tae, Villar Maria T, Artigues Antonio, Lutkenhaus Joe
Abstract excerpt
In Escherichia coli MinE induces MinC/MinD to oscillate between the ends of the cell, contributing to the precise placement of the Z ring at midcell. To do this, MinE undergoes a remarkable conformational change from a latent 6β-stranded form that diffuses in the cytoplasm to an active 4β-stranded form bound to the membrane and MinD. How this conformational switch occurs is not known. Here, using...
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