Optical coherence microscopy as a novel, non-invasive method for the 4D live imaging of early mammalian embryos

Abstract excerpt

Imaging of living cells based on traditional fluorescence and confocal laser scanning microscopy has delivered an enormous amount of information critical for understanding biological processes in single cells. However, the requirement for a high numerical aperture and fluorescent markers still limits researchers' ability to visualize the cellular architecture without causing short- and long-term photodamage....

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