Article
Genetically predicted high body mass index is associated with increased gastric cancer risk.
European journal of human genetics : EJHG - 1 Sept 2017
Mao Yingying, Yan Caiwang, Lu Qun, Zhu Meng, Yu Fei, Wang Cheng, Dai Juncheng, Ma Hongxia, Hu Zhibin, Shen Hongbing, Jin Guangfu
Abstract excerpt
Epidemiological studies have linked body mass index (BMI) with risk of gastrointestinal cancers. However, for gastric cancer, the relationship is more controversial. In particular, it is unclear whether the observed association is due to confounding or bias inherent in conventional observational studies. To investigate whether BMI is causally associated with gastric cancer risk, we applied Mendelian randomization...
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