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Medaka extended one-generation reproduction test evaluating 4-nonylphenol

20 Jun 2017

Abstract excerpt

The medaka extended one-generation test (MEOGRT) was developed as a multigenerational toxicity test for chemicals, particularly endocrine-disrupting chemicals. Briefly, 3 generations of Japanese medaka (Oryzias latipes) are exposed to a chemical over a 20-wk period: 3 wk in the parental generation (F0), 15 wk in the first generation (F1), and 2 wk in the second generation (F2). The present study reports the first...

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PMID: 28631836
DOI: 10.1002/etc.3895

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