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Article

Considerations of developing an NGS assay for clinical applications in precision oncology: The NCI-MATCH NGS assay experience.

Current problems in cancer - 1 Jan 2000

Lih Chih-Jian, Takebe Naoko

Abstract excerpt

Next generation sequencing (NGS) technologies have been widely adapted in clinical oncology by utilizing the profiled genetic mutation information to select patients and to guide the choice of target therapy. To fulfill the regulatory compliance, development of an NGS assay that will be used in clinical trials requires an analytical validation to meet its intend clinical use. NCI-MATCH trial is the largest...

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PMID: 28625332
DOI: 10.1016/j.currproblcancer.2017.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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