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Article

Molecular epidemiology and interferon susceptibility of the natural recombinant hepatitis C virus strain RF1_2k/1b.

The Journal of infectious diseases - 15 Nov 2008

Kurbanov Fuat, Tanaka Yasuhito, Chub Elena, Maruyama Isao, Azlarova Aziza, Kamitsukasa Hiroshi, Ohno Tomoyoshi, Bonetto Stefania, Moreau Isabelle, Fanning Liam J, Legrand-Abravanel Florence, Izopet Jaques, Naoumov Nikolai, Shimada Takashi, Netesov Sergei, Mizokami Masashi

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) genotype is an important determinant of virological response to antiviral therapies. Currently, there are no data available on the molecular epidemiology and interferon susceptibility of the natural intergenotypic recombinant RF1_2k/1b (RF1) strain. METHODS: Genotyping and RF1-PCR screening were performed on samples from 604 HCV RNA-positive individuals from 7 countries....

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PMID: 18928375
DOI: 10.1086/592757

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