Article
Prevalence and Physical Distribution of SRY in the Gonads of a Woman with Turner Syndrome: Phenotypic Presentation, Tubal Formation, and Malignancy Risk.
Hormone research in paediatrics - 1 Jan 2017
Baer Tamar G, Freeman Christopher E, Cujar Claudia, Mansukhani Mahesh, Singh Bahadur, Chen Xiaowei, Abellar Rosanna, Oberfield Sharon E, Levy Brynn
Abstract excerpt
Although monosomy X is the most common karyotype in patients with Turner syndrome, the presence of Y chromosome material has been observed in about 10% of patients. Y chromosome material in patients with Turner syndrome poses an increased risk of gonadoblastoma and malignant transformation. We report a woman with a diagnosis of Turner syndrome at 12 years of age, without signs of virilization, and karyotype...
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