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Article

Disease progression in C9orf72 mutation carriers.

Neurology - 18 Jul 2017

Floeter Mary K, Traynor Bryan J, Farren Jennifer, Braun Laura E, Tierney Michael, Wiggs Edythe A, Wu Tianxia

Abstract excerpt

OBJECTIVE: To assess changes in 3 clinical measures, the Revised ALS Functional Rating Scale (ALSFRS-R), letter fluency, and Frontal Behavioral Inventory (FBI), over time in C9orf72 mutation carriers (C9+) with varied clinical phenotypes. METHODS: Thirty-four unrelated participants with mutations in C9orf72 were enrolled in a prospective natural history study. Participants were classified as asymptomatic,...

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Share to Amyotrophic Lateral Sclerosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28615433
DOI: 10.1212/WNL.0000000000004115
PMCID: PMC5513817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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