Article
Transcriptomic and histopathological analysis of cholangiolocellular differentiation trait in intrahepatic cholangiocarcinoma.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jan 2018
Rhee Hyungjin, Ko Jung Eun, Chung Taek, Jee Byul A, Kwon So Mee, Nahm Ji Hae, Seok Jae Yeon, Yoo Jeong Eun, Choi Jin-Sub, Thorgeirsson Snorri S, Andersen Jesper B, Lee Hye Sun, Woo Hyun Goo, Park Young Nyun
Abstract excerpt
BACKGROUND & AIMS: Intrahepatic cholangiocarcinoma (iCCA) is a heterogeneous entity with diverse aetiologies, morphologies and clinical outcomes. Recently, histopathological distinction of cholangiolocellular differentiation (CD) of iCCA has been suggested. However, its genome-wide molecular features and clinical significance remain unclear. METHODS: Based on CD status, we stratified iCCAs into iCCA with CD...
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