Article
Pathophysiology of antenatal Bartter's syndrome.
Current opinion in nephrology and hypertension - 1 Sept 2017
Kömhoff Martin, Laghmani Kamel
Abstract excerpt
PURPOSE OF REVIEW: Antenatal Bartter syndrome (aBS) is a heterogenous disease resulting from defective ion transport in the thick ascending limb of the loop of Henle. Novel insights into the pathophysiology, as well as the recent identification of a novel genetic cause of aBS, merit an update on this topic. RECENT FINDINGS: In aBS, severe salt losing is further aggravated by defective salt sensing in the macula...
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