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Article

Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells.

Scientific reports - 7 Jun 2017

Piyasena Thisun B H, Setoh Yin X, Hobson-Peters Jody, Newton Natalee D, Bielefeldt-Ohmann Helle, McLean Breeanna J, Vet Laura J, Khromykh Alexander A, Hall Roy A

Abstract excerpt

Flaviviruses such as West Nile virus (WNV), dengue virus and Zika virus are mosquito-borne pathogens that cause significant human diseases. A novel group of insect-specific flaviviruses (ISFs), which only replicate in mosquitoes, have also been identified. However, little is known about the mechanisms of ISF host restriction. We report the generation of infectious cDNA from two Australian ISFs, Parramatta River...

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Source

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Identifiers

PMID: 28592864
DOI: 10.1038/s41598-017-03120-1
PMCID: PMC5462777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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