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In silico identification of potential key regulatory factors in smoking-induced lung cancer

7 Jun 2017

Abstract excerpt

BACKGROUND: Lung cancer is a leading cause of cancer-related death worldwide and is the most commonly diagnosed cancer. Like other cancers, it is a complex and highly heterogeneous disease involving multiple signaling pathways. Identifying potential therapeutic targets is critical for the development of effective treatment strategies. METHODS: We used a systems biology approach to identify potential key...

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PMID: 28592245
DOI: 10.1186/s12920-017-0284-z

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