Article
Arabidopsis JASMONATE-INDUCED OXYGENASES down-regulate plant immunity by hydroxylation and inactivation of the hormone jasmonic acid.
Proceedings of the National Academy of Sciences of the United States of America - 13 Jun 2017
Caarls Lotte, Elberse Joyce, Awwanah Mo, Ludwig Nora R, de Vries Michel, Zeilmaker Tieme, Van Wees Saskia C M, Schuurink Robert C, Van den Ackerveken Guido
Abstract excerpt
The phytohormone jasmonic acid (JA) is vital in plant defense and development. Although biosynthesis of JA and activation of JA-responsive gene expression by the bioactive form JA-isoleucine have been well-studied, knowledge on JA metabolism is incomplete. In particular, the enzyme that hydroxylates JA to 12-OH-JA, an inactive form of JA that accumulates after wounding and pathogen attack, is unknown. Here, we...
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