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NAD+ deficiency primes defense metabolism via 1O2-escalated jasmonate biosynthesis in plants.

Nature communications - 6 Aug 2024

Hong Yechun, Yu Zongjun, Zhou Qian, Chen Chunyu, Hao Yuqiong, Wang Zhen, Zhu Jian-Kang, Guo Hongwei, Huang Ancheng C

Abstract excerpt

Nicotinamide adenine dinucleotide (NAD+) is a redox cofactor and signal central to cell metabolisms. Disrupting NAD homeostasis in plant alters growth and stress resistance, yet the underlying mechanisms remain largely unknown. Here, by combining genetics with multi-omics, we discover that NAD+ deficiency in qs-2 caused by mutation in NAD+ biosynthesis gene-Quinolinate Synthase retards growth but induces...

Topics

Cyclopentanes
Oxylipins
NAD
Arabidopsis
Arabidopsis Proteins
Gene Expression Regulation, Plant
Homeostasis
Animals
Mutation
Lipoxygenase
Glucosinolates

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reactive Oxygen Species

Stress, Physiological

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Identifiers

PMID: 39103368
DOI: 10.1038/s41467-024-51114-1
PMCID: PMC11300881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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