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Millstone: software for multiplex microbial genome analysis and engineering.

Genome biology - 25 May 2017

Goodman Daniel B, Kuznetsov Gleb, Lajoie Marc J, Ahern Brian W, Napolitano Michael G, Chen Kevin Y, Chen Changping, Church George M

Abstract excerpt

Inexpensive DNA sequencing and advances in genome editing have made computational analysis a major rate-limiting step in adaptive laboratory evolution and microbial genome engineering. We describe Millstone, a web-based platform that automates genotype comparison and visualization for projects with up to hundreds of genomic samples. To enable iterative genome engineering, Millstone allows users to design...

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PMID: 28545559
DOI: 10.1186/s13059-017-1223-1
PMCID: PMC5445467

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