Article
Neuromuscular junctions (NMJs): ultrastructural analysis and nicotinic acetylcholine receptor (nAChR) subunit mRNA expression in offspring subjected to protein restriction throughout pregnancy.
International journal of experimental pathology - 1 Apr 2017
Castro Paula Aiello Tomé de Souza, Faccioni Ludimila Canuto, Boer Patrícia Aline, Carvalho Robson Francisco, Matheus Selma Maria Michelin, Dal-Pai-Silva Maeli
Abstract excerpt
Protein restriction during gestation can alter the skeletal muscle phenotype of offspring; however, little is known with regard to whether this also affects the neuromuscular junction (NMJ), as muscle phenotype maintenance depends upon NMJ functional integrity. This study aimed to evaluate the effects of a low protein (6%) intake by dams throughout gestation on male offspring NMJ morphology and nicotinic...
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