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Determination of SCN1A genetic variants in Mexican patients with refractory epilepsy and Dravet syndrome.

Genetics and molecular research : GMR - 18 May 2017

Jiménez-Arredondo R E, Brambila-Tapia A J L, Mercado-Silva F M, Magaña-Torres M T, Figuera L E

Abstract excerpt

Mutations in the SCN1A gene can result in syndromes associated with epilepsy, including the Dravet syndrome (DS). However, the prevalence of such mutations in these diseases varies widely between different studies, and has not been examined in Mexican patients with epilepsy. Therefore, the objective of this study was to determine the frequency of SCN1A mutations (in the exon 26) in a cohort of Mexican patients...

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Case-Control Studies
Child
Child, Preschool
Drug Resistant Epilepsy
Epilepsies, Myoclonic

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PMID: 28525652
DOI: 10.4238/gmr16029405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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