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Article

Surgery in Focal Congenital Hyperinsulinism (CHI) - The "Hyperinsulinism Germany International" Experience in 30 Children.

Pediatric endocrinology reviews : PER - 1 Dec 2016

Barthlen Winfried, Varol Emine, Empting Susann, Wieland Ilse, Zenker Martin, Mohnike Wolfgang, Vogelgesang Silke, Mohnike Klaus

Abstract excerpt

OBJECTIVES: Results of surgery for focal CHI in 30 children PATIENTS AND METHODS: All showed an ABCC8 or KCNJ11 mutation. After PET/CT in 29 children and PET/MRT in 1 case, frozen-section guided resection was performed, in left-sided cases by laparoscopy. Mean age at surgery was 11.7 months (2-49). RESULTS: In 28/30 children, the PET/CT or MRT correlated with histopathology. In two cases, a focal lesion was...

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Identifiers

PMID: 28508606
DOI: 10.17458/PER.2016.BVE.Surgeryinfocal

Genes

ABCC8
KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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